Genetic rescue of functional senescence in synaptic and behavioral plasticity.

Citation data:

Sleep, ISSN: 1550-9109, Vol: 37, Issue: 9, Page: 1427-37

Publication Year:
2014
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Repository URL:
https://escholarship.umassmed.edu/infdis_pp/168; https://works.bepress.com/neal_silverman/65
PMID:
25142573
DOI:
10.5665/sleep.3988; sp-00735-13
PMCID:
PMC4153059
Author(s):
Donlea, Jeffrey M.; Ramanan, Narendrakumar; Silverman, Neal S.; Shaw, Paul J.
Publisher(s):
Oxford University Press (OUP)
Tags:
Medicine; Cellular and Molecular Physiology; Molecular and Cellular Neuroscience; Molecular Genetics
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article description
Aging has been linked with decreased neural plasticity and memory formation in humans and in laboratory model species such as the fruit fly, Drosophila melanogaster. Here, we examine plastic responses following social experience in Drosophila as a high-throughput method to identify interventions that prevent these impairments.