Polyglycolide/polylactide-coated platinum coils for patients with ruptured and unruptured cerebral aneurysms: a single-center experience.

Citation data:

Stroke, ISSN: 1524-4628, Vol: 36, Issue: 9, Page: 1948-53

Publication Year:
2005
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Citations 52
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Repository URL:
https://escholarship.umassmed.edu/oapubs/1653
PMID:
16051893
DOI:
10.1161/01.str.0000177532.94736.85
Author(s):
Linfante, Italo; Akkawi, Nabil M.; Perlow, Alain; Andreone, Vincenzo; Wakhloo, Ajay K.
Publisher(s):
Ovid Technologies (Wolters Kluwer Health)
Tags:
Medicine; Neuroscience; Adult; Aged; Aneurysm, Ruptured; Biocompatible Materials; Cerebral Angiography; Cohort Studies; Embolization, Therapeutic; Female; Follow-Up Studies; Humans; Inflammation; Intracranial Aneurysm; Male; Middle Aged; Pilot Projects; Polyesters; Polyglycolic Acid; Polymers; Prospective Studies; Recurrence; Time Factors; Treatment Outcome; Life Sciences; Medicine and Health Sciences
article description
Recanalization of cerebral aneurysm is a limitation of bare platinum coils (BPCs). In a swine aneurysm model, polyglycolide/polylactide (a polymer)-coated platinum coils (Matrix) accelerated clot fibrosis and reduced recanalization rate and aneurysmal volume. We aimed to evaluate the safety of Matrix coils in patients with intracranial aneurysm.