Polyglycolide/polylactide-coated platinum coils for patients with ruptured and unruptured cerebral aneurysms: a single-center experience.
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Stroke, ISSN: 1524-4628, Vol: 36, Issue: 9, Page: 1948-53
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- Medicine; Neuroscience; Adult; Aged; Aneurysm, Ruptured; Biocompatible Materials; Cerebral Angiography; Cohort Studies; Embolization, Therapeutic; Female; Follow-Up Studies; Humans; Inflammation; Intracranial Aneurysm; Male; Middle Aged; Pilot Projects; Polyesters; Polyglycolic Acid; Polymers; Prospective Studies; Recurrence; Time Factors; Treatment Outcome; Life Sciences; Medicine and Health Sciences
Recanalization of cerebral aneurysm is a limitation of bare platinum coils (BPCs). In a swine aneurysm model, polyglycolide/polylactide (a polymer)-coated platinum coils (Matrix) accelerated clot fibrosis and reduced recanalization rate and aneurysmal volume. We aimed to evaluate the safety of Matrix coils in patients with intracranial aneurysm.