Resting-state functional connectivity changes within the default mode network and the salience network after antipsychotic treatment in early-phase schizophrenia.

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Neuropsychiatric disease and treatment, ISSN: 1176-6328, Vol: 13, Page: 397-406

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Wang, Yingchan; Tang, Weijun; Fan, Xiaoduo; Zhang, Jianye; Geng, Daoying; Jiang, Kaida; Zhu, Dianming; Song, Zhenhua; Xiao, Zeping; Liu, Dengtang
Dove Medical Press Ltd.
Medicine; Neuroscience; antipsychotics; default network; fMRI; salience network; schizophrenia; Mental Disorders; Neuroscience and Neurobiology; Psychiatric and Mental Health; Psychiatry
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article description
Abnormal resting-state functional connectivity (FC), particularly in the default mode network (DMN) and the salience network (SN), has been reported in schizophrenia, but little is known about the effects of antipsychotics on these networks. The purpose of this study was to examine the effects of atypical antipsychotics on DMN and SN and the relationship between these effects and symptom improvement in patients with schizophrenia.