Greater lifetime estrogen exposure protects cognition, while hormone replacement therapy taken at menopause has no cognitive effects at all.
Impact of Type 2 Diabetes and Postmenopausal Hormone Therapy on Incidence of Cognitive Impairment in Older Women.
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Diabetes care, ISSN: 1935-5548, Vol: 38, Issue: 12, Page: 2316-24
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- Medicine; Nursing; Endocrinology, Diabetes, and Metabolism; Obstetrics and Gynecology; Psychiatry and Psychology; Women's Health
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In older women, higher levels of estrogen may exacerbate the increased risk for cognitive impairment conveyed by diabetes. We examined whether the effect of postmenopausal hormone therapy (HT) on cognitive impairment incidence differs depending on type 2 diabetes.