Implementing trials of complex interventions in community settings: the USC-Rancho Los Amigos pressure ulcer prevention study (PUPS).
- Citation data:
Clinical trials (London, England), ISSN: 1740-7753, Vol: 11, Issue: 2, Page: 218-29
- Publication Year:
- Repository URL:
- PMC3972348; 3972348
- ClinicalTrials.gov Identifier:
- Pharmacology, Toxicology and Pharmaceutics; Medicine and Health Sciences
Randomized trials of complex, non-pharmacologic interventions implemented in home and community settings, such as the University of Southern California (USC)-Rancho Los Amigos National Rehabilitation Center (RLANRC) Pressure Ulcer Prevention Study (PUPS), present unique challenges with respect to (1) participant recruitment and retention, (2) intervention delivery and fidelity, (3) randomization and assessment, and (4) potential inadvertent treatment effects.