Implementing trials of complex interventions in community settings: the USC-Rancho Los Amigos pressure ulcer prevention study (PUPS).

Citation data:

Clinical trials (London, England), ISSN: 1740-7753, Vol: 11, Issue: 2, Page: 218-29

Publication Year:
2014
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Repository URL:
https://hsrc.himmelfarb.gwu.edu/smhs_crl_facpubs/39
PMID:
24577972
DOI:
10.1177/1740774514521904
PMCID:
PMC3972348; 3972348
ClinicalTrials.gov Identifier:
NCT01999816
Author(s):
Clark, Florence; Pyatak, Elizabeth A; Carlson, Mike; Blanche, Erna Imperatore; Vigen, Cheryl; Hay, Joel; Mallinson, Trudy; Blanchard, Jeanine; Unger, Jennifer B; Garber, Susan L; Diaz, Jesus; Florindez, Lucia I; Atkins, Michal; Rubayi, Salah; Azen, Stanley Paul; PUPS Study Group Show More Hide
Publisher(s):
SAGE Publications
Tags:
Pharmacology, Toxicology and Pharmaceutics; Medicine and Health Sciences
article description
Randomized trials of complex, non-pharmacologic interventions implemented in home and community settings, such as the University of Southern California (USC)-Rancho Los Amigos National Rehabilitation Center (RLANRC) Pressure Ulcer Prevention Study (PUPS), present unique challenges with respect to (1) participant recruitment and retention, (2) intervention delivery and fidelity, (3) randomization and assessment, and (4) potential inadvertent treatment effects.