Elevated serum phosphate levels are associated with decreased amputation-free survival after interventions for critical limb ischemia.

Citation data:

Journal of vascular surgery, ISSN: 1097-6809, Vol: 65, Issue: 2, Page: 431-437

Publication Year:
2017
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Repository URL:
https://hsrc.himmelfarb.gwu.edu/smhs_surgery_facpubs/503
PMID:
27667151
DOI:
10.1016/j.jvs.2016.06.097
Author(s):
Zettervall, Sara L; Soden, Peter A; Ultee, Klaas H J; Seldon, Crystal; Oh, Jinhee; McGann, Kevin; Schermerhorn, Marc L; Guzman, Raul J
Publisher(s):
Elsevier BV; Mosby-Year Book
Tags:
Medicine; Aged; Aged; 80 and over; Amputation; Biomarkers; Boston; Critical Illness; Disease-Free Survival; Endovascular Procedures; Female; Humans; Hyperphosphatemia; Ischemia; Kaplan-Meier Estimate; Limb Salvage; Male; Middle Aged; Phosphates; Proportional Hazards Models; Recurrence; Retrospective Studies; Risk Factors; Time Factors; Treatment Outcome; Up-Regulation; Vascular Surgical Procedures; Aged; Aged, 80 and over; Amputation; Biomarkers; Boston; Critical Illness; Disease-Free Survival; Endovascular Procedures; Female; Humans; Hyperphosphatemia; Ischemia; Kaplan-Meier Estimate; Limb Salvage; Male; Middle Aged; Phosphates; Proportional Hazards Models; Recurrence; Retrospective Studies; Risk Factors; Time Factors; Treatment Outcome; Up-Regulation; Vascular Surgical Procedures; Surgery
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article description
Elevated serum phosphate levels have been associated with increased risks of cardiovascular events and death in several patient populations. The effects of serum phosphate on outcomes in patients with critical limb ischemia (CLI) have not been evaluated. In this study, we assessed the effect of abnormal phosphate levels on mortality and major limb events after surgical intervention for CLI.