Immunostimulatory nucleic acid molecules

Publication Year:
2010

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Repository URL:
https://ir.uiowa.edu/patents/511; https://ir.uiowa.edu/cgi/viewcontent.cgi?article=1510&context=patents
Author(s):
Krieg, Arthur M.; Kline, Joel; Klinman, Dennis; Steinberg, Alfred D.
Publisher(s):
United States Patent and Trademark Office
patent description
Nucleic acids containing unmethylated CpG dinucleotides and therapeutic utilities based on their ability to stimulate an immune response and to redirect a Th2 response to a Th1 response in a subject are disclosed. Methods for treating atopic diseases, including atopic dermatitis, are disclosed.