Fine-tuning the predicted position of genes associated with economic traits in livestock

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Vol: 650, Issue: 1

Publication Year:
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Grapes, L.; Firat, M. Z.; Dekkers, Jack C.M.; Rothschild, Max F.; Fernando, Rohan L.
Iowa State University
ASL R1947; Agriculture; Animal Sciences
report description
Different methods that estimate the position of a gene on a chromosome were tested in computer-simulated populations to determine their accuracy. Given the same amount of genetic information from the animals, one method performed better than the others. In situations where experimental costs were assumed to be equal but genetic information could vary, this method was no longer the most accurate. Further study of this method found that the animals’ genetic information must be used in a specific way in order to obtain the most accurate position of the gene. These methods will be useful in identifying genes and the genetic differences between animals that can be used for genetic improvement of livestock.