A polyanhydride-based implantable single dose vaccine platform for long-term immunity.

Citation data:

Vaccine, ISSN: 1873-2518, Vol: 36, Issue: 7, Page: 1024-1025

Publication Year:
2018
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Repository URL:
https://lib.dr.iastate.edu/vpath_pubs/104
PMID:
29413093
DOI:
10.1016/j.vaccine.2017.11.067
Author(s):
Schaut, Robert G.; Brewer, Matt T.; Mendoza, Kriscelle; Jackman, John K.; Narasimhan, Balaji; Jones, Douglas E.
Publisher(s):
Elsevier BV
Tags:
Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Veterinary; Medicine
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article description
Traditionally, immune priming followed by an antigen-boost is utilized for vaccine-induced protective immunity and maintaining long-term immunity often requires repeated exposure to antigen. Here, a novel single dose vaccination platform designed with gonadotropin releasing hormone multiple antigenic peptide as a model antigen is shown.