Molecular network and chemical fragment-based characteristics of medicinal herbs with cold and hot properties from Chinese medicine.

Citation data:

Journal of ethnopharmacology, ISSN: 1872-7573, Vol: 148, Issue: 3, Page: 770-9

Publication Year:
2013
Usage 422
Abstract Views 403
Link-outs 19
Captures 68
Readers 35
Exports-Saves 33
Social Media 42
Shares, Likes & Comments 34
Tweets 8
Citations 16
Citation Indexes 16
Repository URL:
https://repository.hkbu.edu.hk/hkbu_staff_publication/1779
PMID:
23702041
DOI:
10.1016/j.jep.2013.04.055
Author(s):
Liang, Fei; Li, Li; Wang, Maolin; Niu, Xuyan; Zhan, Junping; He, Xiaojuan; Yu, Changyuan; Jiang, Miao; Lu, Aiping
Publisher(s):
Elsevier BV; Elsevier
Tags:
Pharmacology, Toxicology and Pharmaceutics; Bioinformatics; Herbal medicine; Ingenuity Pathway Analysis; Property; Tradition Chinese medicine
Most Recent Tweet View All Tweets
article description
Chinese herbal medicines (HMs) is one of the great herbal systems of the world, which play an important role in current health care system in many countries. In the view of tradition Chinese medicine (TCM) theory, Yin-yang and five-elements theory is the central theory, which is used to explain how the world and body work. Under the guidance of such philosophy, TCM considers that HMs have different properties, which are the important factors for prescribing herbal formulae; such prescriptions are based on TCM pattern classification in clinical practice. The cold and hot property are commonly defined for HM property identification; however, the biological activities that are related to the HM property remain a mystery because of a lack of appropriate methods. A bioinformatics approach was applied to identify the distinguishing biological activities of HMs that have these cold and hot properties.