TLR-4 may mediate signaling pathways of Astragalus polysaccharide RAP induced cytokine expression of RAW264.7 cells.

Citation data:

Journal of ethnopharmacology, ISSN: 1872-7573, Vol: 179, Page: 243-52

Publication Year:
2016
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Citations 33
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Repository URL:
https://repository.hkbu.edu.hk/scmd_ja/21
PMID:
26743224
DOI:
10.1016/j.jep.2015.12.060
Author(s):
Wei, Wei; Xiao, Hai-Tao; Bao, Wan-Rong; Ma, Dik-Lung; Leung, Chung-Hang; Han, Xiao-Qiang; Ko, Chun-Hay; Lau, Clara Bik-San; Wong, Chun-Kwok; Fung, Kwok-Pui; Leung, Ping-Chung; Bian, Zhao-Xiang; Han, Quan-Bin Show More Hide
Publisher(s):
Elsevier BV; Elsevier
Tags:
Pharmacology, Toxicology and Pharmaceutics; Astragalus polysaccharides; RAW264.7 macrophages; MAPKs; NF-κB; Medicine and Health Sciences
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article description
Polysaccharides of Radix Astragali (Astragalus membranaceus (Fisch) Bge.; Huangqi) are able to induce cytokine production of macrophages and are considered the main active ingredient for the immune-enhancing effect of this commonly used medicinal herb.