Effect of antioxidant supplementation on exercise-induced cardiac troponin release in cyclists: a randomized trial.

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PloS one, ISSN: 1932-6203, Vol: 8, Issue: 11, Page: e79280

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10.1371/journal.pone.0079280; 10.1371/journal.pone.0079280.g001; 10.1371/journal.pone.0079280.g002; 10.1371/journal.pone.0079280.t001
PMC3834092; 3834092
ClinicalTrials.gov Identifier:
Lieke J. J. Klinkenberg; Peter T. Res; Guido R. Haenen; Aalt Bast; Luc J. C. van Loon; Marja P. van Dieijen-Visser; Steven J.R. Meex; Stephen L. Atkin
Public Library of Science (PLoS); Public Library of Science; Figshare
Biochemistry, Genetics and Molecular Biology; Agricultural and Biological Sciences; Biological Sciences; antioxidant; supplementation; exercise-induced; cardiac; troponin; randomized; Human and Clinical Nutrition; ck; hscrp; concentrations; pre-; post-supplementation
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Cardiac troponin is the biochemical gold standard to diagnose acute myocardial infarction. Interestingly however, elevated cardiac troponin concentrations are also frequently observed during and after endurance-type exercise. Oxidative stress associated with prolonged exercise has been proposed to contribute to cardiac troponin release. Therefore, the aim of this study was to assess the effect of 4 week astaxanthin supplementation (a potent cartenoid antioxidant) on antioxidant capacity and exercise-induced cardiac troponin release in cyclists.