Three-dimensional ex vivo system

Publication Year:
Usage 30
Downloads 18
Abstract Views 12
Repository URL:
Burg, Karen J. L.; Yang, Chih-chao
patent number 8293531
patent description
Disclosed are three-dimensional (3D) systems as may be utilized for ex vivo tissue or cell growth and development. A system generally includes a base material and at least one wicking fiber embedded therein through which a liquid can be spontaneously drawn by capillary action. Wicking fibers can define a plurality of colinear channels along the exterior surface of the axial length of the fiber. Wicking fibers can be present in disclosed systems as individual fibers or in bundles. Disclosed systems can be useful in various scientific studies, including, but not limited to, drug discovery, vaccine development, cell biology studies, and biomaterial development.