Borrelia infection and risk of celiac disease.

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BMC medicine, ISSN: 1741-7015, Vol: 15, Issue: 1, Page: 169

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Alaedini, Armin; Lebwohl, Benjamin; Wormser, Gary P; Green, Peter H; Ludvigsson, Jonas F
Springer Nature; Touro Scholar
Medicine; Borrelia burgdorferi; Celiac disease; Infection; Inflammation; Lyme disease; Medicine and Health Sciences
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article description
Environmental factors, including infectious agents, are speculated to play a role in the rising prevalence and the geographic distribution of celiac disease, an autoimmune disorder. In the USA and Sweden where the regional variation in the frequency of celiac disease has been studied, a similarity with the geographic distribution of Lyme disease, an emerging multisystemic infection caused by Borrelia burgdorferi spirochetes, has been found, thus raising the possibility of a link. We aimed to determine if infection with Borrelia contributes to an increased risk of celiac disease.