Borrelia burgdorferi induces a type I interferon response during early stages of disseminated infection in mice.
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BMC microbiology, ISSN: 1471-2180, Vol: 16, Issue: 1, Page: 29
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- Repository URL:
- https://touroscholar.touro.edu/nymc_fac_pubs/93; https://touroscholar.touro.edu/cgi/viewcontent.cgi?article=1092&context=nymc_fac_pubs
- Immunology and Microbiology; Medicine; Lyme disease; Type I interferon; bacterial pathogenesis; mouse model; Animals; Borrelia burgdorferi; Disease Models, Animal; Female; Humans; Interferon Type I; Lyme Disease; Male; Mice; Mice, Inbred C3H; Bacteriology; Microbiology
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Lyme borrelia genotypes differ in their capacity to cause disseminated disease. Gene array analysis was employed to profile the host transcriptome induced by Borrelia burgdorferi strains with different capacities for causing disseminated disease in the blood of C3H/HeJ mice during early infection.