Phosphorylation of PCNA by EGFR inhibits mismatch repair and promotes misincorporation during DNA synthesis.
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Proceedings of the National Academy of Sciences of the United States of America, ISSN: 1091-6490, Vol: 112, Issue: 18, Page: 5667-72
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- Multidisciplinary; Medicine; Cell Line; Tumor; Cell Proliferation; Colorectal Neoplasms; DNA; DNA Mismatch Repair; Disease Progression; Genome; Human; HeLa Cells; Humans; Microscopy; Fluorescence; Models; Molecular; Mutation; Neoplasms; Phosphorylation; Proliferating Cell Nuclear Antigen; Protein Binding; Receptor; Epidermal Growth Factor; Sequence Analysis; Tyrosine; Oncology