PlumX Metrics
Embed PlumX Metrics

Perineural invasion and laryngeal squamous cell carcinoma: a systematic review

Brazilian Journal of Otorhinolaryngology, ISSN: 1808-8694, Vol: 91, Issue: 1, Page: 101519
2025
  • 0
    Citations
  • 0
    Usage
  • 2
    Captures
  • 0
    Mentions
  • 0
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

Review Description

Several studies have evaluated the prognostic significance of Perineural Invasion (IPN) in laryngeal cancer; however, the results are non-conclusive. Therefore, we conducted a meta-analysis aiming to identify the prognostic value of IPN in laryngeal cancer. A literature review was performed, searching MedLine via PubMed, Scielo, Lilacs, Cochrane and Websco. RevMan 5.4 was used for the statistical analysis. A total of 19 laryngeal cancer studies were included. The results indicate that IPN in laryngeal cancer shows 2-year survival with RR 0.71 (0.59‒0.86); disease-free survival RR 0.51 (0.14–1.95); and locoregional recurrence RR 1.71 (1.25–2.35). IPN is a negative prognostic factor in laryngeal cancer.

Provide Feedback

Have ideas for a new metric? Would you like to see something else here?Let us know