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Serological response to bovine herpesvírus 1 and 5 and bovine viral diarrea virus induced by comercial vaccines

Ciencia Rural, ISSN: 1678-4596, Vol: 45, Issue: 1, Page: 58-63
2014
  • 18
    Citations
  • 10,716
    Usage
  • 41
    Captures
  • 3
    Mentions
  • 0
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    18
    • Citation Indexes
      18
  • Usage
    10,716
  • Captures
    41
  • Mentions
    3
    • News Mentions
      3
      • News
        3

Most Recent News

Immunogenicity in sheep of Uruguayan commercial vaccines against bovine alphaherpesvirus 1, 5 and bovine pestiviruses/Imunogenicidade em ovelhas de vacinas comerciais Uruguaias para alfaherpesvirus bovino 1, 5 e pestivirus de bovinos.(MICROBIOLOGY texto e

INTRODUCTION Cattle rising has economic importance in the countries of South America, particularly Uruguay, Brazil and Argentina. This region has a large cattle herd, with

Article Description

This study evaluated the immunogenicity of vaccines for bovine herpesvirus 1 and 5 (BoHV-1/5) and viral diarrhea virus 1 and 2 (BVDV-1/2) available in the Brazilian market. Calves were divided into groups (10-12), vaccinated twice with a 30 days interval. Samples collected 30 days after the second dose were submitted to virus neutralization test against BoHV-1, BoHV-5, BVDV-1 and BVDV-2. With the exception of two vaccines that induced seroconversion in 8/10 and 9/10 of the animals, the other induced antibodies against BoHV-1 in all vaccinated animals (geometric mean titers [GMTs] 1.7 and 4.8) and four induced antibodies against BoHV-5 in all animals (GMTs 1.0 to 4.2), whereas three vaccines induced partial seroconversion (5/10, 6/10 and 7/10 animals). Only one vaccine induced antibody response to BVDV-1 in all vaccinated animals (GMT=6.7). Partial seroconversion to BVDV-1 was detected in four vaccine (6/10, GMT 4.0; 6/10, GMT 5.6 and 4/10, GMT 1.8). A vaccine induced response in only one animal and three vaccines did not induce antibodies against BVDV-1 in any animal. Antibodies to BVDV-2 were detected only in three vaccine groups, and partly (10/10, GMT 6.5; 5/10, GMT 1.6 and 2/10, GMT 1.0). Five vaccines did not induce antibodies to BVDV-2 in any of the animals. Results demonstrate that the BoHV-1 component of commercial vaccines seems to have acceptable immunogenicity. However, the BVDV component of most vaccines does not induce consistent response against BVDV-1, especially, to BVDV-2. It is evident that strategies for production of vaccines, particularly to BVDV must be urgently revised.

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