Submicroscopic placental malaria: Histopathology and expression of physiological process mediators
Revista Peruana de Medicina Experimental y Salud Publica, ISSN: 1726-4642, Vol: 37, Issue: 2, Page: 220-228
2020
- 11Citations
- 31Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations11
- Citation Indexes11
- 11
- Captures31
- Readers31
- 18
- 13
Article Description
Objetives: To relate histopathological events of placental malaria (PM), immune cell behavior and gene expression associated with cytokines, hypoxia, inflammation and angiogenesis in placentas with or without plasmodial infection. Materials and methods: Transversal design, with three independent groups. Women were recruited, and their placentas were collected in 2009-2016, in the hospitals of Puerto Libertador and Tierralta, northwestern Colombia. The sample size was defined by convenience. The malaria diagnosis was based on real-time quantitative PCR. Results: We studied 20 cases of PM by P. vivax (PM-V), 20 cases of PM by P. falciparum (PM-F) and 19 without PM; 95% of the cases of PM are submicroscopic placental plasmodial infection (SPPI). The three groups differ in frequency and number of histopathological events. Physiological process mediators showed significant difference between groups, except IL-2, VEGF, VEGFR-1 and C5a. Conclusions: Infected placentas are clearly different from uninfected ones. P. vivax behaves as pathogenic as P. falciparum. The approximation to the integral approach of the problem of PM is underlined. Submicroscopic placental plasmodial infection causes tissue and physiological mediator alterations as does microscopic infection, although probably to a lesser degree.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85088928020&origin=inward; http://dx.doi.org/10.17843/rpmesp.2020.372.4759; http://www.ncbi.nlm.nih.gov/pubmed/32876209; https://rpmesp.ins.gob.pe/index.php/rpmesp/article/view/4759; http://www.scielo.org.pe/scielo.php?script=sci_arttext&pid=S1726-46342020000200220&lng=en&tlng=en; http://www.scielo.org.pe/scielo.php?script=sci_abstract&pid=S1726-46342020000200220&lng=en&tlng=en; http://www.scielo.org.pe/scielo.php?script=sci_arttext&pid=S1726-46342020000200220; http://www.scielo.org.pe/scielo.php?script=sci_abstract&pid=S1726-46342020000200220; http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S1726-46342020000200220&lng=en&tlng=en; http://www.scielosp.org/scielo.php?script=sci_abstract&pid=S1726-46342020000200220&lng=en&tlng=en; http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S1726-46342020000200220; http://www.scielosp.org/scielo.php?script=sci_abstract&pid=S1726-46342020000200220; https://dx.doi.org/10.17843/rpmesp.2020.372.4759; https://rpmesp.ins.gob.pe/index.php/rpmesp/article/view/4759/3709; https://rpmesp.ins.gob.pe/index.php/rpmesp/article/download/4759/3654; https://rpmesp.ins.gob.pe/index.php/rpmesp/article/view/4759/3757; https://rpmesp.ins.gob.pe/index.php/rpmesp/article/download/4759/3676
Instituto Nacional de Salud (Peru)
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