Clonal dissemination of KPC-2 in carbapenem resistant Klebsiella pneumoniae
Infectio, ISSN: 2422-3794, Vol: 24, Issue: 1, Page: 42-49
2020
- 2Citations
- 1,102Usage
- 35Captures
Metric Options: CountsSelecting the 1-year or 3-year option will change the metrics count to percentiles, illustrating how an article or review compares to other articles or reviews within the selected time period in the same journal. Selecting the 1-year option compares the metrics against other articles/reviews that were also published in the same calendar year. Selecting the 3-year option compares the metrics against other articles/reviews that were also published in the same calendar year plus the two years prior.
Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Article Description
Objective: To determine the mechanism of antibiotic resistance and molecular epidemiology of carbapenem resistant isolates of Klebsiella pneumoniae. Materials and Methods: 30 multidrug resistant isolates of K. pneumoniae were obtained from urine culture, tracheal aspirate, wound secretion, bladder catheter, blood culture, peritoneal fluid, catheter tip, abdominal collection, and bronchial secretion. K. pneumoniae isolates were collected between November 2012 and April 2013. Identification and susceptibility were determined by the VITEK 2 system. Resistance genes were identified by PCR, sequence type (ST) was established by multilocus sequence typing (MLST), and clonal relationship was defined by pulsed field gel electrophoresis (PFGE). Results: All isolates were multidrug resistant and susceptible to colistin and tigecycline. 100% of isolates produced KPC-2 carbapenemase. This study detected Extended Spectrum Β-Lactamases enconding genes. 67% of isolates were positive for bla-M, 100% were positive for bla, and 93% of isolates were positive for bla. Analysis of the clonal relationship clustered 20 isolates in the same clonal complex. Multilocus sequence typing showed the predominant sequence type ST 258 in 60% of population. ST 1199 were present in 20% of bacterial population. Conclusion: Molecular epidemiology, clinical research and molecular biology studies improve understanding of mechanisms of resistance distribution among bacteria of clinical interest.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85082945992&origin=inward; http://dx.doi.org/10.22354/in.v24i1.826; http://revistainfectio.org/P_OJS/index.php/infectio/article/view/826; http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S0123-93922020000100042&lng=en&tlng=en; http://www.scielo.org.co/scielo.php?script=sci_abstract&pid=S0123-93922020000100042&lng=en&tlng=en; http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S0123-93922020000100042; http://www.scielo.org.co/scielo.php?script=sci_abstract&pid=S0123-93922020000100042; https://dx.doi.org/10.22354/in.v24i1.826
Asociacion Colombiana de Infectologia - ACIN
Provide Feedback
Have ideas for a new metric? Would you like to see something else here?Let us know