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RET gene mutational diagnosis and precision medicine in Mexico

Gaceta Medica de Mexico, ISSN: 0016-3813, Vol: 158, Issue: 3, Page: 160-166
2022
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Article Description

Precision medicine is a reality in some diseases; it supports the development of accurate and specific diagnostic methods, new drugs and molecules. Our research team in Mexico, made up of clinical and biomedical researchers, has been performing free RET gene mutational diagnosis for medullary thyroid cancer and multiple endocrine neoplasia (MEN) 2 and 3 for 20 years. RET pathogenic variants in the Mexican population are consistent with reported data: most common mutations are 634/NEM2 and 918/NEM3. Currently, new nanobiotechnology methods are being developed for this type of determination in order to obtain faster, simpler, more sensitive and specific results applicable in all types of laboratories.

Bibliographic Details

Martínez-Castillo, Mariana A; Zárate, María E Medrano-Ortiz de; Valenzuela-Pérez, Alejandra; Ruiz-Romero, Jorge A; Quijano-Castro, Félix O; Salcedo, Mauricio

Publicidad Permanyer, SLU

Medicine

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