Daptomycin in combination with other antibiotics for the treatment of complicated methicillin-resistant Staphylococcus aureus bacteremia.

Citation data:

Clinical therapeutics, ISSN: 1879-114X, Vol: 36, Issue: 10, Page: 1303-16

Publication Year:
2014
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PMID:
25444563
DOI:
10.1016/j.clinthera.2014.09.005
Author(s):
Dhand, Abhay; Sakoulas, George
Publisher(s):
Elsevier BV
Tags:
Pharmacology, Toxicology and Pharmaceutics; Medicine
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review description
Methicillin-resistant Staphylococcus aureus (MRSA) has emerged as one of the most important nosocomial pathogens. Resistance to antibiotic therapy has been known to emerge especially in clinically complex scenarios, resulting in challenges in determining optimal treatment of serious MRSA. Daptomycin, in combination with other antibiotics, has been successfully used in the treatment of these infections, with the aims of resulting in reducing the prevention of antimicrobial resistance and increased killing compared with daptomycin monotherapy.