Ghrelin and eating disorders.

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Progress in neuro-psychopharmacology & biological psychiatry, ISSN: 1878-4216, Vol: 40, Issue: 1, Page: 70-82

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PMC3522761; 3522761
Atalayer, Deniz; Gibson, Charlisa; Konopacka, Alexandra; Geliebter, Allan
Elsevier BV; Touro Scholar
Pharmacology, Toxicology and Pharmaceutics; Neuroscience; Anorexia nervosa; Bulimia nervosa; Binge eating disorder; Des-acyl ghrelin; Ghrelin; Neuroscience and Neurobiology; Psychiatric and Mental Health
review description
There is growing evidence supporting a multifactorial etiology that includes genetic, neurochemical, and physiological components for eating disorders above and beyond the more conventional theories based on psychological and sociocultural factors. Ghrelin is one of the key gut signals associated with appetite, and the only known circulating hormone that triggers a positive energy balance by stimulating food intake. This review summarizes recent findings and several conflicting reports on ghrelin in eating disorders. Understanding these findings and inconsistencies may help in developing new methods to prevent and treat patients with these disorders.