EETs Elicit Direct Increases in Pulmonary Arterial Pressure in Mice.

Citation data:

American journal of hypertension, ISSN: 1941-7225, Vol: 29, Issue: 5, Page: 598-604

Publication Year:
2016
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PMID:
26304959
DOI:
10.1093/ajh/hpv148
PMCID:
PMC5014081
Author(s):
Kandhi, Sharath; Froogh, Ghezal; Qin, Jun; Luo, Meng; Wolin, Michael S.; Huang, An; Sun, Dong
Publisher(s):
Oxford University Press (OUP)
Tags:
Medicine
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article description
The biological role of epoxyeicosatrienoic acids (EETs) in the regulation of pulmonary circulation is currently under debate. We hypothesized that EETs initiate increases in right ventricular systolic pressure (RVSP) via perhaps, pulmonary vasoconstriction.