Prothrombin Time and Activated Partial Thromboplastin Time Testing: A Comparative Effectiveness Study in a Million-Patient Sample.

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PloS one, ISSN: 1932-6203, Vol: 10, Issue: 8, Page: e0133317

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10.1371/journal.pone.0133317; 10.1371/journal.pone.0133317.t004; 10.1371/journal.pone.0133317.g002; 10.1371/journal.pone.0133317.g001; 10.1371/journal.pone.0133317.g004; 10.1371/journal.pone.0133317.g005; 10.1371/journal.pone.0133317.g003; 10.1371/journal.pone.0133317.t003
PMC4532488; 4532488
Manu N. Capoor; Jerry L. Stonemetz; John C. Baird; Fahad S. Ahmed; Ahsan Awan; Christof Birkenmaier; Mario A. Inchiosa; Steven K. Magid; Kathryn McGoldrick; Ernesto Molmenti; Sajjad Naqvi; Stephen D. Parker; S. M. Pothula; Aryeh Shander; R. Grant Steen; Michael K. Urban; Judith Wall; Vincent A. Fischetti; Sinuhe Hahn Show More Hide
Public Library of Science (PLoS); Figshare
Biochemistry, Genetics and Molecular Biology; Agricultural and Biological Sciences; Biological Sciences; lupus anticoagulant antibodies; comparative effectiveness study; aptt tests; prothrombin time; von willebrand disease; screening tests; american healthcare expenditures; activated partial thromboplastin time testing; partial thromboplastin time; pt tests; preoperative patients
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A substantial fraction of all American healthcare expenditures are potentially wasted, and practices that are not evidence-based could contribute to such waste. We sought to characterize whether Prothrombin Time (PT) and activated Partial Thromboplastin Time (aPTT) tests of preoperative patients are used in a way unsupported by evidence and potentially wasteful.