Turn-on and Turn-off Fluorescent Probes for Carbon Monoxide Detection and Blood Carboxyhemoglobin Determination.

Citation data:

ACS sensors, ISSN: 2379-3694, Vol: 3, Issue: 6, Page: 1102-1108

Publication Year:
2018
Captures 13
Readers 13
Social Media 4
Tweets 4
Repository URL:
http://scholarworks.unist.ac.kr/handle/201301/24417
PMID:
29767518
DOI:
10.1021/acssensors.8b00083
Author(s):
Shi, Genggongwo; Yoon, Taeseung; Cha, Seoncheol; Kim, Seulgi; Yousuf, Muhammad; Ahmed, Nisar; Kim, Doseok; Kang, Hyun-Wook; Kim, Kwang S.
Publisher(s):
American Chemical Society (ACS); AMER CHEMICAL SOC
Tags:
Chemical Engineering; Physics and Astronomy; azidocarbonylation; blood carboxyhemoglobin; carbon monoxide; fluorescent probe; gas sensing
Most Recent Tweet View All Tweets
article description
Water-soluble, carbazole-based two-photon excitable fluorescent probes MPVC-I ("turn-on") and MPVC-II ("turn-off") are rationally designed and synthesized for the selective monitoring of carbon monoxide (CO). Both probes can effectively measure carboxyhemoglobin (HbCO) in the blood of the animals exposed to a CO dose as low as 100 ppm for 10 min. The palladium catalyzed azidocarbonylation reaction was optimized to improve the sensing efficiency.