Wearable smart sensor systems integrated on soft contact lenses for wireless ocular diagnostics.

Citation data:

Nature communications, ISSN: 2041-1723, Vol: 8, Page: 14997

Publication Year:
2017
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Repository URL:
http://scholarworks.unist.ac.kr/handle/201301/21889
PMID:
28447604
DOI:
10.1038/ncomms14997
Author(s):
Kim, Joohee, Kim, Minji, Lee, Mi-Sun, Kim, Kukjoo, Ji, Sangyoon, Kim, Yun-Tae, Park, Jihun, Na, Kyungmin, Bae, Kwi-Hyun, Kyun Kim, Hong, Bien, Franklin, Young Lee, Chang, Park, Jang-Ung Show More Hide
Publisher(s):
Springer Nature, NATURE PUBLISHING GROUP
Tags:
Electronic devices, Sensors and biosensors
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article description
Wearable contact lenses which can monitor physiological parameters have attracted substantial interests due to the capability of direct detection of biomarkers contained in body fluids. However, previously reported contact lens sensors can only monitor a single analyte at a time. Furthermore, such ocular contact lenses generally obstruct the field of vision of the subject. Here, we developed a multifunctional contact lens sensor that alleviates some of these limitations since it was developed on an actual ocular contact lens. It was also designed to monitor glucose within tears, as well as intraocular pressure using the resistance and capacitance of the electronic device. Furthermore, in-vivo and in-vitro tests using a live rabbit and bovine eyeball demonstrated its reliable operation. Our developed contact lens sensor can measure the glucose level in tear fluid and intraocular pressure simultaneously but yet independently based on different electrical responses.