Laminar stream of detergents for subcellular neurite damage in a microfluidic device: a simple tool for the study of neuroregeneration.
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Journal of neural engineering, ISSN: 1741-2552, Vol: 10, Issue: 3, Page: 036020
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- Engineering; Neuroscience; Acetylcholinesterase; Aplysia californica; Experimental platform; Mechanical tension; Micro-fluidic devices; Migration distance; Neuronal regenerations; Neurotrophic factors
The regeneration and repair of damaged neuronal networks is a difficult process to study in vivo, leading to the development of multiple in vitro models and techniques for studying nerve injury. Here we describe an approach for generating a well-defined subcellular neurite injury in a microfluidic device.