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Various factors influencing the signal intensity of oligonucleotides in electrospray mass spectrometry

Biological Mass Spectrometry, ISSN: 1096-9888, Vol: 23, Issue: 6, Page: 320-322
1994
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Article Description

The quality of electrospray mass spectra of oligonucleotides often suffers from the low signal intensity and clustering with metal ions. This sometimes makes an exact determination of the molecular masses impossible. We describe here several factors contributing to these effects and show some means for their improvement. Copyright © 1994 John Wiley & Sons, Ltd.

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