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Prevention of adhesion and promotion of pseudoislets formation from a β-cell line by fluorocarbon emulsions

ChemBioChem, ISSN: 1439-4227, Vol: 7, Issue: 8, Page: 1160-1163
2006
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Article Description

So far, but no further. A perfluorocarbon (PFC) emulsion induces formation of pseudoislets from MIN6 b-cells that, in the absence of PFC, form a monolayer. MIN6 pseudoislets secrete insulin under glucose stimulation and have potential in the therapy of type-1 diabetes. In addition, PFC emulsions are expected to facilitate islet graft survival, owing to their oxygen-carrying capacity. © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.

Bibliographic Details

Sanchez Dominguez, Margarita; Maillard, Elisa; Krafft, Marie Pierre; Sigrist, Séverine; Belcourt, Alain

Wiley

Biochemistry, Genetics and Molecular Biology; Chemistry

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