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Efficient synthesis of 1,2,4-triazolo[4,3-a][1,8]naphthyridines under microwave irradiation

Journal of Heterocyclic Chemistry, ISSN: 0022-152X, Vol: 46, Issue: 1, Page: 124-126
2009
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  • Citations
    3
    • Citation Indexes
      3

Article Description

A simple and highly efficient procedure has been described for the synthesis of 6-aryl-9-(4-phenox-phenyl)-1,2,4-triazolo [4,3-a] [1,8] napthyridines (4) by the oxidation of 4-phenoxybenzaldehyde 3-aryl-1,8- naphthyridin-2-ylhydrazones (3) with chloramines-T in methanol under microwave irradiation. The products were obtained in very good yields and excellent purities. © 2009 HeteroCorporation.

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