A novel retinal biomarker for Parkinson's disease: Quantifying the foveal pit with optical coherence tomography
Movement Disorders, ISSN: 1531-8257, Vol: 30, Issue: 12, Page: 1692-1695
2015
- 22Citations
- 50Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations22
- Citation Indexes22
- 22
- CrossRef14
- Captures50
- Readers50
- 50
Article Description
Background: Optical coherence tomography offers a potential biomarker tool in Parkinson's disease (PD). A mathematical model quantifying symmetry, breadth, and depth of the fovea was applied. Methods: Nintey-six subjects (72 PD and 24 healthy controls) were included in the study. Macular scans of each eye were obtained on two different optical coherence tomography devices: Cirrus and RTVue. Results: The variables corresponding to the cardinal gradients of the fovea were the most sensitive indicators of PD for both devices. Principal component analysis distinguished 65% of PD patients from controls on Cirrus, 57% on RTVue. Conclusion: Parkinson's disease shallows the superior/inferior and to a lesser degree nasal-temporal foveal slope. The symmetry, breadth, and depth model fits optical coherence tomography data derived from two different devices, and it is proposed as a diagnostic tool in PD.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84944448930&origin=inward; http://dx.doi.org/10.1002/mds.26411; http://www.ncbi.nlm.nih.gov/pubmed/26340519; https://onlinelibrary.wiley.com/doi/10.1002/mds.26411; http://doi.wiley.com/10.1002/mds.26411; http://onlinelibrary.wiley.com/doi/10.1002/mds.26411/abstract
Wiley
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