Splenectomy and spontaneous remission in children with chronic idiopathic thrombocytopenic purpura
Pediatric Blood and Cancer, ISSN: 1545-5009, Vol: 47, Issue: 5 SUPPL., Page: 737-739
2006
- 23Citations
- 19Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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- Citations23
- Citation Indexes22
- 22
- CrossRef16
- Clinical Citations1
- PubMed Guidelines1
- Captures19
- Readers19
- 19
Review Description
Two hundred thirty of 696 evaluable children were identified as having chronic idiopathic thrombocytopenic purpura (ITP). Splenectomy was performed in 30 (13%), achieving remission in 22 (73%). Favorable response was associated to higher initial platelet count. Spontaneous remission was achieved by 53/200 non-splenectomized patients (26.5%), up to 10 years from diagnosis. More than half of them recovered between 6th and 12th month from diagnosis. The recovery rate was significantly higher (P = 0.03) in children aged <9 years (31.2%) than in older children (14.6%). No reliable factor predictive of response in individual cases is still available. © 2006 Wiley-Liss, Inc.
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