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Highly Focused Clonal Composition of CD8 + CD28 neg T Cellsin Aqueous Humor of Fuchs Heterochromic Cyclitis

Experimental Eye Research, ISSN: 0014-4835, Vol: 75, Issue: 3, Page: 317-325
2002
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Article Description

Fuchs heterochromic cyclitis (FHC) is characterized by a predominant CD8 + T cell subset infiltrating the anterior chamber, but the clonal composition of these T cells is unknown. In the present study, T cell repertoire diversity of the accumulating T cells was analyzed to investigate if a high degree of restriction could indicate antigen-driven immune response.

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