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Pertussis: Identification, Prevention and Control

Advances in Experimental Medicine and Biology, ISSN: 2214-8019, Vol: 1183, Page: 127-136
2019
  • 11
    Citations
  • 0
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  • 18
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  • 0
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Metric Options:   Counts1 Year3 Year

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Book Chapter Description

Pertussis is a vaccine-preventable disease. Despite the high vaccination coverage among children, pertussis is considered a re-emerging disease for which identification, prevention and control strategies need to be improved. To control pertussis it is important to maintain a high vaccination coverage to protect the age groups considered at high risk for the disease. Laboratory confirmation of Bordetella pertussis infection together with a differential diagnostic test for other Bordetellae are prerequisite for a correct and timely diagnosis of pertussis. Moreover, investigations of antimicrobial susceptibility and whole genome sequencing may permit to monitor the circulation of antimicrobials resistant and/or vaccine-escape strains. Finally, the preventive framework should no longer consider pertussis exclusively as a childhood infectious disease, since adults may play a role in transmission events.

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