Immediate early genes and the mapping of environmental representations in hippocampal neural networks
Immediate Early Genes in Sensory Processing, Cognitive Performance and Neurological Disorders, Page: 159-176
2006
- 2Citations
- 15Captures
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Book Chapter Description
The hippocampus has received much attention by researchers interested in understanding the nature of "declarative" or "explicit" memory-the memory for discrete events, which requires conscious recollection of disparate facts. These memories, such as remembering one's wedding day or last vacation, serve to define us as individuals, and consequently are of critical importance in human life. The ability to rapidly form explicit memories, such as remembering the location of a food source or an encounter with a predator, can also be necessary for the survival of an animal. In studies from rodents, primates, and humans, the hippocampus has been shown repeatedly to be important for the formation and consolidation of declarative memories (Zola-Morgan and Squire, 1993; Suzuki and Eichenbaum, 2000). For this reason, the hippocampus is arguably the most studied region of the brain. The disparate approaches used to understanding hippocampal function include the study of neural plasticity in hippocampal slice and dissociated neural cultures, lesion/pharmacological experiments in behaving rodents, electrophysiological recordings in rodents and primates, and human functional neuroimaging. Despite years of research across these domains, we still have much to learn as to how neurons of the hippocampus facilitate the formation and consolidation of long-term memories.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=50349091500&origin=inward; http://dx.doi.org/10.1007/978-0-387-33604-6_9; http://link.springer.com/10.1007/978-0-387-33604-6_9; http://link.springer.com/content/pdf/10.1007/978-0-387-33604-6_9.pdf; https://dx.doi.org/10.1007/978-0-387-33604-6_9; https://link.springer.com/chapter/10.1007/978-0-387-33604-6_9; http://www.springerlink.com/index/10.1007/978-0-387-33604-6_9; http://www.springerlink.com/index/pdf/10.1007/978-0-387-33604-6_9
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