Released N-Glycan Analysis for Biotherapeutic Development Using Liquid Chromatography and Mass Spectrometry
Methods in Molecular Biology, ISSN: 1940-6029, Vol: 2261, Page: 35-53
2021
- 1Citations
- 5Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations1
- Citation Indexes1
- Captures5
- Readers5
Book Chapter Description
In this chapter, we describe an LC-fluorescence (FLR)/MS-based method for released N-glycan analysis in the development of biotherapeutic proteins. The method includes enzymatic release and labeling of N-glycans with a signal-enhancing tag, LC-MS data collection, and data interpretation. Using the given protocol, up to 24 glycan samples can be prepared within 1 h, while the LC-FLR/MS data can be collected and analyzed using an established data processing method in a semi-automated manner.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85099721320&origin=inward; http://dx.doi.org/10.1007/978-1-0716-1186-9_4; http://www.ncbi.nlm.nih.gov/pubmed/33420983; http://link.springer.com/10.1007/978-1-0716-1186-9_4; https://dx.doi.org/10.1007/978-1-0716-1186-9_4; https://link.springer.com/protocol/10.1007/978-1-0716-1186-9_4
Springer Science and Business Media LLC
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