Regulation of Gene Expression Using dCas9-SunTag Platforms
Methods in Molecular Biology, ISSN: 1940-6029, Vol: 2577, Page: 189-195
2023
- 4Citations
- 7Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations4
- Citation Indexes4
- Captures7
- Readers7
Book Chapter Description
Regulating gene expression is important for basic research and therapeutic applications. The epigenome is a record of genetic modifications such as DNA methylation and histone modifications, and epigenetic changes can play a key role in modifying gene expression. With the advent of genome editing technologies, it has become possible to manipulate the epigenome of specific genomic regions to control gene expression. In particular, CRISPR–Cas9 systems have been used widely for epigenome editing due to their high efficiency, versatility, specificity, and ease of use. Here, we describe a protocol for the upregulation of specific genes using the dCas9-SunTag system.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85139378337&origin=inward; http://dx.doi.org/10.1007/978-1-0716-2724-2_13; http://www.ncbi.nlm.nih.gov/pubmed/36173574; https://link.springer.com/10.1007/978-1-0716-2724-2_13; https://dx.doi.org/10.1007/978-1-0716-2724-2_13; https://link.springer.com/protocol/10.1007/978-1-0716-2724-2_13
Springer Science and Business Media LLC
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