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Measuring the Full-Field Electroretinogram in Rodents

Methods in Molecular Biology, ISSN: 1940-6029, Vol: 2708, Page: 131-140
2023
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Book Chapter Description

Electroretinography allows for noninvasive functional assessment of the retina and is a mainstay for preclinical studies of retinal function in health and disease. The full-field electroretinogram is useful for a variety of applications as it returns a functional readout from each of the major cell classes within the retina: photoreceptors, bipolar cells, amacrine cells, and retinal ganglion cells. Rodent models are commonly employed in ocular degeneration studies due to the fast throughput of these mammalian species and the conservation of the electroretinogram from the preclinic to the clinic. Here we describe approaches for in vivo electroretinography in rodent models.

Bibliographic Details

Lee, Pei Ying; Zhao, Da; Wong, Vickie H Y; Hoang, Anh; Tran, Katie K N; van Koeverden, Anna K; Afiat, Brianna C; Nguyen, Christine T O; Bui, Bang V

Springer Science and Business Media LLC

Biochemistry, Genetics and Molecular Biology

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