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Information analysis on depression in patients with Parkinson's disease

Lecture Notes in Electrical Engineering, ISSN: 1876-1100, Vol: 217 LNEE, Issue: VOL. 2, Page: 253-259
2013
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Conference Paper Description

Objective: To investigate the relationship between depression and clinical aspects of Parkinson's disease (PD). Methods: 318 patients diagnosed by the London Brain Bank criteria took part in the investigation. 318 PD patients were evaluated using United Parkinson's Disease Rating Scale (UPDRS), Hoehn & Yahr staging (H&Y). Depression was evaluated with Zung's Self-Rating Depression Scale (SDS). The analysis of quantitative data was performed using descriptive statistics, ANOVA and χtest. Results: 208 (65.4 %) patients were depressed. There was a significant difference between men and women PD patients respect to the depression degree (χ = 16.981, P < 0.05); depression degree among duration groups were statistically significant different (χ = 18.0, P < 0.05); when compared to the non-depressed ones, presented the following results: H&Y: 2.34 ± 0.851 versus 1.83 ± 0.725; UPDRS total: 50.486 ± 23.787 versus 38.191 ± 16.081. Conclusion: Depression is a frequently neuropsychiatric phenomenon in Parkinson's disease. Female and long duration PD patients has higher incidence of moderate and severe depression. PD patients with depressive disorder presented more advanced H&Y staging, greater UPDRS score than non-depressed ones. © 2013 Springer-Verlag.

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