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Vaccine delivery systems for veterinary immunization

Mucosal Delivery of Biopharmaceuticals: Biology, Challenges and Strategies, Vol: 9781461495246, Page: 379-406
2014
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Book Chapter Description

Animal health includes different areas such as companion animals, livestock and also, animal-to-human transmission from both domestic animals and wildlife. Diversity management has led to different approaches to the development of veterinary vaccines. This chapter exposes an update of vaccine achievements, focusing on nonliving subunit vaccine strategies and the forthcoming tactics surrounding this approach. Particularly, it explores several aspects of the employment of immunoadjuvants, focusing on micro- or nanoparticulate delivery systems. Thus, we will analyze these delivery systems and the elicited immune responses considering particular veterinary vaccine requirements. Experimental vaccination against brucellosis will be used here as a model. In conclusion, the use of appropriate antigens together with the right adjuvants may offer safety, efficacy, and more convenient delivery methods for animal vaccination campaigns.

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