PlumX Metrics
Embed PlumX Metrics

Preparation of a two-photon fluorescent probe for imaging HO in lysosomes in living cells and tissues

Methods in Molecular Biology, ISSN: 1064-3745, Vol: 1594, Page: 129-139
2017
  • 2
    Citations
  • 0
    Usage
  • 4
    Captures
  • 0
    Mentions
  • 0
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

Book Chapter Description

Hydrogen peroxide (HO) plays important roles in many physiological and pathological processes. At the cellular organelle level, the abnormal concentrations of HO in the lysosomes may cause redox imbalance and the loss of the critical functions of the lysosomes. Herein, we describe the preparation of a potent lysosome-targeted two-photon fluorescent probe (Lyso-HP) for the detection of HO in the lysosomes in the living cells. This unique fluorescent probe can also be employed to effectively detect HO in the living tissues using two-photon fluorescence microscopy.

Provide Feedback

Have ideas for a new metric? Would you like to see something else here?Let us know