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Association of single nucleotide polymorphisms in selenoprotein genes with cancer risk

Methods in Molecular Biology, ISSN: 1064-3745, Vol: 1661, Page: 313-324
2018
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  • 14
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Book Chapter Description

Genetic association studies have linked genetic variants in the Selenium (Se) metabolism with the development of complex diseases such as cancer and helped unravel novel mechanisms underlying cancer development. The chapter describes the specificity of genetic variants in the Se metabolism, the approaches used in association studies, and the limitations of such approaches.

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