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Micronucleus Assay with Tetrad Cells of Tradescantia

Methods in Molecular Biology, ISSN: 1940-6029, Vol: 2031, Page: 325-335
2019
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Book Chapter Description

The Tradescantia micronucleus assay has been used since 50 years for the detection of genotoxins (including carcinogens) in the environment. A large database concerning the effects of individual chemicals and complex environmental mixtures (soil, air and waters) has accumulated. In contrast to other mutagenicity test systems, the effects of low concentrations of heavy metals, radionuclides, certain herbicides, pesticides and gaseous mutagens can be detected and it is also possible to conduct in situ biomonitoring studies with plant. The test system has been validated and standardized protocols have been developed for laboratory experiments and for field studies which are described in this chapter.

Bibliographic Details

Mišík, Miroslav; Pichler, Clemens; Rainer, Bernhard; Nersesyan, Armen; Mišíková, Katarína; Knasmueller, Siegfried

Springer Science and Business Media LLC

Biochemistry, Genetics and Molecular Biology

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