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Standardization in synthetic biology

Methods in Molecular Biology, ISSN: 1064-3745, Vol: 813, Page: 23-43
2012
  • 38
    Citations
  • 0
    Usage
  • 104
    Captures
  • 0
    Mentions
  • 2
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    38
  • Captures
    104
  • Social Media
    2
    • Shares, Likes & Comments
      2
      • Facebook
        2

Book Chapter Description

Synthetic Biology is founded on the idea that complex biological systems are built most effectively when the task is divided in abstracted layers and all required components are readily available and well-described. This requires interdisciplinary collaboration at several levels and a common understanding of the functioning of each component. Standardization of the physical composition and the description of each part is required as well as a controlled vocabulary to aid design and ensure interoperability. Here, we describe standardization initiatives from several disciplines, which can contribute to Synthetic Biology. We provide examples of the concerted standardization efforts of the BioBricks Foundation comprising the request for comments (RFC) and the Registry of Standardized Biological parts as well as the international Genetically Engineered Machine (iGEM) competition. © 2012 Springer Science+Business Media, LLC.

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