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Diagnostic applications of nuclear medicine: Vulvar cancer

Nuclear Oncology: From Pathophysiology to Clinical Applications, Page: 1115-1138
2022
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Book Chapter Description

Vulvar cancer is an uncommon malignancy in women and is less frequently seen as compared to cervical or endometrial cancer. Human papillomavirus (HPV) infection, chronic lichen simplex infection, and genital warts are considered some of the predisposing factors. While metastases occur in late-stage disease (usually via lymphatic spread), most lesions are detected in the early stages. Anatomic imaging is the mainstay for evaluation of local extent. [F]FDG PET/CT imaging has incremental value for evaluation of equivocal lesions, assessing nodal status, and detecting distant metastasis. Lymphoscintigraphy for sentinel node mapping is useful for surgical planning and limiting postoperative morbidity from extensive nodal dissection. This chapter summarizes the current status and emerging trends in imaging vulvar cancer using radiopharmaceuticals.

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