Biochanin A Chemistry, Structural Modifications, and Therapeutic Applications: An Update
Bioprospecting of Tropical Medicinal Plants, Page: 789-805
2023
- 2Citations
- 6Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Book Chapter Description
Natural products (NPs) will continue to provide humans with an unrivaled source of innovative medication leads and inspiration for non-natural drug synthesis. Because our scientific understanding of nature is continuously developing, it would be useful to acquaint the scientific community and the general public with the pharmacological characteristics of NPs. Flavonoids have long attracted scientists interest due to their structural diversity and biological activities. Biochanin A, a bioactive isoflavone ingredient derived from Trifolium pratense (red clover) and a variety of other legumes, has grabbed researchers’ interest in recent years due to its broad range of pharmacological effects including neuroprotective, antioxidant, osteogenic, antihyperglycemic, anti-inflammatory, anticancer, and antihyperglycemic properties. Biochanin A targets numerous signal transduction pathways involved in cell proliferation, cell differentiation, and apoptosis to demonstrate its molecular activities. Moreover, it inhibits Akt and mitogen-activated protein kinases (MAPKs) activity in cancer cells. This review highlights the source, chemistry, structural modifications, and therapeutic potential of biochanin A, as well as the molecular targets via which it displays various biological functions.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85177727283&origin=inward; http://dx.doi.org/10.1007/978-3-031-28780-0_32; https://link.springer.com/10.1007/978-3-031-28780-0_32; https://dx.doi.org/10.1007/978-3-031-28780-0_32; https://link.springer.com/chapter/10.1007/978-3-031-28780-0_32
Springer Science and Business Media LLC
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