The liver as an immune-privileged site
Infection, Immune Homeostasis and Immune Privilege, Page: 93-106
2012
- 4Citations
- 5Captures
Metric Options: CountsSelecting the 1-year or 3-year option will change the metrics count to percentiles, illustrating how an article or review compares to other articles or reviews within the selected time period in the same journal. Selecting the 1-year option compares the metrics against other articles/reviews that were also published in the same calendar year. Selecting the 3-year option compares the metrics against other articles/reviews that were also published in the same calendar year plus the two years prior.
Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Book Chapter Description
The liver is well known as an organ with important functions in the metabolism of lipids, proteins, and carbohydrates. Besides these functions, it is getting increasingly clear that the liver has also a central role in initiating and modulating immune responses. Special attention is linked to the fact that 75% of the liver's blood supply comes as venous blood from the gut, not only rich in nutrients but also rich in microbial degradation products. To protect the organ and the body from these immunostimulatory microbial products, the liver has an extraordinary scavenger function clearing all these molecules. At the same time, the liver itself is protected by establishing a tolerogenic state by modulating immune responses. Adaptive and innate immune reactions are suppressed to avoid unnecessary immune activation. Here we describe the parenchymal and non-parenchymal cell populations contributing to the tolerogenic status. An organ that represses immune reactions is a well-suited target for pathogens. Here we describe the viral pathogens targeting the liver, their infection behavior, and potential therapeutic options.
Bibliographic Details
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85029554803&origin=inward; http://dx.doi.org/10.1007/978-3-0348-0445-5_4; https://link.springer.com/10.1007/978-3-0348-0445-5_4; https://dx.doi.org/10.1007/978-3-0348-0445-5_4; https://link.springer.com/chapter/10.1007/978-3-0348-0445-5_4; http://www.springerlink.com/index/10.1007/978-3-0348-0445-5_4; http://www.springerlink.com/index/pdf/10.1007/978-3-0348-0445-5_4
Springer Science and Business Media LLC
Provide Feedback
Have ideas for a new metric? Would you like to see something else here?Let us know