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Wound inflammation: Emerging role of miRNA

MicroRNAs and Other Non-Coding RNAs in Inflammation, Page: 139-151
2015
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Book Chapter Description

Wound inflammation occurs in response to injury. It is a coordinated process involving tissues, cells, and an array of soluble, cell-associated, and intracellular factors. The role of certain microRNAs in wound healing and inflammation, in particular (a key process underpinning wound healing), has emerged in recent years. Here, mechanisms involving inflammatory cells, secreted molecules, and miRNAs that can affect wound healing are reviewed. Of interest miR-155, miR-146a, and miR-21, among others, have been shown to have a number of specialized roles in the inflammatory process, Toll-like receptor signaling, and efferocytosis. Other important miRNAs that regulate inflammation are also discussed.

Bibliographic Details

Amitava Das; Scott Chaffee; Chandan K. Sen; Sashwati Roy

Springer Science and Business Media LLC

Medicine; Immunology and Microbiology; Biochemistry, Genetics and Molecular Biology

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