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Melanoma epidemiology and prevention

Cancer Treatment and Research, ISSN: 0927-3042, Vol: 167, Page: 17-49
2016
  • 111
    Citations
  • 0
    Usage
  • 137
    Captures
  • 1
    Mentions
  • 11
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    111
  • Captures
    137
  • Mentions
    1
    • Blog Mentions
      1
      • 1
  • Social Media
    11
    • Shares, Likes & Comments
      11
      • Facebook
        11

Most Recent Blog

What Is the Link Between Sun Exposure and Melanoma?

Scientists have recognized a link between sun exposure and melanoma for at least a century (Cancer Epidemiology, June 2017). On the other hand, the relationship is not quite straightforward. Back in the late 20th century, researchers proposed an intermittent exposure hypothesis. The idea was that brief, periodic exposures to strong sunlight (perhaps resulting in sunburn) triggered the changes init

Book Chapter Description

The epidemiology of melanoma is complex, and individual risk depends on sun exposure, host factors, and genetic factors, and in their interactions as well. Sun exposure can be classified as intermittent, chronic, or cumulative (overall) exposure, and each appears to have a different effect on type of melanoma. Other environmental factors, such as chemical exposures—either through occupation, atmosphere, or food—may increase risk for melanoma, and this area warrants further study. Host factors that are well known to be important are the numbers and types of nevi and the skin phenotype. Genetic factors are classified as high-penetrant genes, moderate-risk genes, or low-risk genetic polymorphisms. Subtypes of tumors, such as BRAF-mutated tumors, have different risk factors as well as different therapies. Prevention of melanoma has been attempted using various strategies in specific subpopulations, but to date optimal interventions to reduce incidence have not emerged.

Bibliographic Details

Buller D.B.; Berwick M.; Cust A.E.; Veierod M.B.; Cust A.; Thomas N.E.; Gallagher R.P.; Meyskens Jr F.L.; Meyskens F.L.; Lee T.K.; Gallagher R.; Meyskens Jr. F.L.; Berwick, Marianne; Buller, David B.; Cust, Anne; Gallagher, Richard; Lee, Tim K.; Meyskens, Frank; Pandey, Shaily; Thomas, Nancy E.; Veierød, Marit B.; Ward, Sarah

Springer Science and Business Media LLC

Medicine; Biochemistry, Genetics and Molecular Biology

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